Chem 201

Instructor:  Dr. Annie Bianchino

5 units

Office 411-10

 

Office phone:  (714)  992-7436

 

email:  abianchino@fullcoll.edu

 

 

 

Course Description:  approximately 9 hours in-class time divided into lecture, problem solving, and lab.  This course is designed for students who wish to pursue careers in the Allied Health professions, but all interested students are welcome.  After a review of organic chemistry, the principles of biochemistry will be discussed as they relate to medicine and health.

 

Prerequisites:  Chem 101 or the equivalent with a grade of C or better.  If you have not taken Chem 101, discuss your situation with the instructor immediately.

 

Required Materials:

Texts:       General, Organic, & Biological Chemistry: Structures of Life, by Timberlake, Pearson/Benjamin Cummings publisher, 4th ed., 2013. 

                Mastering Chemistry Online Homework with this text.

                Biochemistry Class Notes & Labs, Dr. Annie Bianchino.

 

Supplies:  Scientific Calculator  (with scientific notation and logs)

                  Safety Goggles for Lab

                  Fullerton College Computer Access

 

Typical Grading Policy: 

 

 

 

Exams, 4 @ 100 pts each

400

Quizzes and Homework    (100 pts each)

200

Laboratory  (100 lab reports,  100 quizzes)

200

Final Exam (cumulative)

200

 

 

Total

1000

 

 

Generally, there will be NO MAKE UP EXAMS.  See the instructor if an emergency situation keeps you from missing an exam.

 

 

Tentative assignment of letter grades.

 

lowest A

900 pts (90%)

lowest B

800 pts (80%)

lowest C

680 pts (68%)

lowest D

550 pts (55%)

anything below 550 pts =  F

 


Other information and guidelines:

            Cell phones, etc.  Please turn off anything that may beep you and disturb the class.  If you need to have it on, place it in vibrate mode and quietly leave the room if you need to answer. 

NO TEXTING in class!  NO goofing off online either.  The classroom should be a quiet learning environment with minimal distractions.  Do not do anything that may disturb others who are trying to focus and learn.

            Attendance is mandatory for success.  Missing even 1 lecture may result in your being “hopelessly lost” and confused for the rest of the semester.  Missing 2 or more lectures may result in the instructor dropping you from the course.  However, do not rely on the instructor drop option.  It is your responsibility to drop the class if you want to.  (If you want me to drop you, let me know in writing).

            Review old material as quickly as possible, preferably directly after class.  Write abbreviated review notes for future study.

            Write down notes as you study.  Don’t just look over the material; writing helps you to understand it.

            Preview new work, even if you simply look at the pictures and read section headings in the chapter and class notes.

            Study on a regular basis, not just before exams.  DO NOT CRAM! 

            Quizzes on lecture material will be announced the day before the quiz.  The quiz may be given during lecture or lab hours.

            Lab quizzes are pop quizzes, and will always be given at the start of lab.  If you miss it, you get a zero.

            Homework problems (from text or handouts or computer) will be assigned and these will be collected and graded (partly).  Keep up to date with your homework assignments.  LATE (on paper) homework will not be grades; you will receive a score of 50% for late homework.  If you must miss class, get the assignment in to me earlier, or on that date (by 2 pm) via my mailbox.

            Go to the tutoring center or see a PAL for (free) help as soon as you realize you need it.

            Use the Study Area section of the Mastering Chemistry software.

            Use your time wisely, remember, there are no make up exams, and deadlines for handing in homework will be strictly enforced.

            Be prepared for the laboratory experiment.  Read the experiment before lab; it will save you time and frustration and you will get a better grade!

            Organize a study group.  However, always study alone first before meeting with the group.  You will see how much better it works.

            Finally, CHEATING WILL NOT BE TOLERATED.  Do not collaborate with others on exams or any assignments that are graded.  This includes lab reports.  If cheating is suspected, a grade of zero will be given to all involved students.  Cheating on an exam may result in receiving an F in the course and/or dismissal from Fullerton College.  Using notes (cheat-sheets) or looking at others' papers is cheating.  This is a serious offense.

 

Important Dates – look these up each semester:

After 2 weeks

Last day to ADD classes

After 2 weeks

Last day to DROP without a “W”

Around the 12th week

Last day to DROP classes  (W on transcript)

 

*Regarding the late drop deadline:  This instructor firmly believes it is best to decide whether or not to remain enrolled in any course as early as possible during the semester.  You should know way before the 14th week whether or not you should drop the course.  For those of you who are transferring to Universities, they often have much shorter drop deadlines.  To help you make the decision to drop, you should consider your performance on each quiz and especially exams.  Discuss any concerns you have with me immediately so that we can determine how to remedy the situation.  If you receive a graded exam/quiz that has “see me” written by the grade, then you must come to my office hours (or make other arrangements to meet with me) to discuss your poor performance on that exam.  Do not be shy or embarrassed, I do this to identify reasons for the performance and to find ways to improve the situation before it gets out of hand (ie, you receive too many failing grades so that you cannot pass the course). 


 

 

Chem 201

Tentative Lecture Schedule

 

Week

Topic

Chapter

 

I.  Molecules of Life

 

  1

Introduction and Review

Organic Chemistry Review (hydrocarbons)

 

11 & 12

 

  2

Organic Chem Review continued (alcohols, aldehydes, ketones)

13 & 14

 

  3

Organic Chemistry Review (amines, carboxylic acid & derivatives)

 

Stereochemistry-chiral molecules

16 & 18

(omit sec 18.6)

14.5

 

  4

Acid, Bases, & pH & Buffers

10

 

  5

AminoAcids (begin new section)

EXAM 1

19

 

II.  Protease Inhibitors and AIDS

 

  6

Amino Acids and Proteins

19

 

  7

Enzymes and coenzymes and vitamins

20

 

III.  “You are what you eat”

 

  8

Solutions (mostly review)

Bioenergetics (begin new section)

8

22.1-22.3

 

  9

Carbohydrate Structure and Reactions

EXAM 2

15

 

IV.  Diabetes and other Metabolic Disorders

 

  10

Digestion, Carbohydrate Metabolism I

22.4-22.8

 

  11

Carbohydrate Metabolism II

23

 

  12

Lipids

Lipid Metabolism

EXAM 3  

17

 

  13

Lipid and Nitrogen Metabolism

Overview of metabolism. Diabetes

24.1-24.5

24.6-24.10

 

  14

EXAM 4

Begin Molecular Biology:  DNA, RNA, proteins

Thanksgiving Holiday

*,  21

 

V.  Hello Dolly,  GMO (Genetically Modified Organisms), Gene Therapy...

 

  15

Molecular Biology I:   DNA, RNA, proteins

Molecular Biology II:  gene expression, recombinant DNA, viruses

 

21

 

  16

Molecular Biology II: continued.

FINAL EXAM  (cumulative starting from biochem)

21,*

 


 

 

 

Chem. 201 Student Learning Outcomes:               

 

        I.      Upon successful completion of the course students will be able to apply proper procedures and regulations for safe handling and use of chemicals in the laboratory.

 

Assessment:  lab safety quiz, safety questions from lab final exam.

 

 

      II.      Upon successful completion of the course students will be able to recognize and describe the chemical structures and biological functions of carbohydrates, lipids, proteins, and nucleic acids.

 

Assessment:  quizzes on specific biomolecules, Exam questions on structure/function relationships.

 

 

   III.      Upon successful completion of the course students will be able to demonstrate quantitative skills for chemical problem solving by applying critical thinking and mathematical operations to chemical data.

 

Assessment:  quiz on solutions, solutions problems on Exam 2 or final exam, quiz on enzyme kinetics, or enzyme kinetics problem on final exam.

 

 

 


 

Chemistry 201

On-line Homework

Electronic homework can be accessed 24/7 and will provide you with instantaneous feedback as you do your homework on-line. You will be graded and given credit for the homework done on-line. All the assignments and due dates can be found at the www.masteringchemistry.com web site. You will be able to access the electronic homework with your "access code" found with the textbook: General, Organic, & Biological Chemistry: Structures of Life, by Timberlake, Prentice Hall publisher, 4th ed., 2013.

You may already have a Mastering Chemistry Account from chem. 101.  If so, login to that account and then add the class.  Click on Enroll in a new course after logging in. Select I am taking a course...and need to enroll in my instructor's course. Boxes will appear where you can type in your Course ID.

l Course ID :  MCBIANCHINO*****

l Student ID:  (your Fullerton College Student ID#.)

 

 

To Log on for the very first time, please do the following:

I) Registration for first time students:

  1. Go to www.masteringchemistry.com
  2. Under Register Click on “Students”.
  3. Click on  “Yes, I have an access code” and “continue” box.
  4. Read the License Agreement and click on " I Accept" button.
  5. Fill out Access Information. Click to answer the question, “Do you have a Pearson Education account?” Click No if you do not have one from another class. Fill out log in name and password that you created. Write them down on this piece of paper! Enter access code in the six blank boxes provided.
  6. Fill in Account Information pertaining to Personal Information, School Location, Security Questions, Confirmation and Summary.

 

II) First Time Log In:

1.   Log in to MasteringChemistry. Go to www.masteringchemistry.com and click on SIGN IN.  Enter the login name and password you created during Registration, and click Sign In.

2.   You will need two pieces of information:

l Course ID : MCBIANCHINO*****

l Student ID: (your Fullerton College Student ID#.)

3.   Enter the Course ID, then Student ID and click Save.

That’s it.  You are now enrolled in your Instructor’s Course.

Support and More Information:

1     Click the Assignment List tab on the left to view the Introduction to MasteringChemistry assignment. This assignment will teach you how to use the program.

2     Online Help link is available on the site.

3     For registration questions only: visit http://247pearsoned.custhelp.com/app/answers/detail/a_id/10613

4     For all other questions: visit  www.masteringchemistry.com/support   

5     To check browser requirements (especially to view certain interactive tutorials and animations), click the Check Browser link from the MasteringChemistry Home page.

 

 

Chem 201

Homework Assignments

Timberlake Text (4th edition)

Chapter #

Problems to be entered via MasteringChemistry on the website.

Note additional problems/tutorials are also on the website.

Problems to be written/drawn on paper and handed in during class

11

5,11,15,16,18,29,30,31,32,35,40,59,61a

19,22,27,47,48,49,54,56,70

12

2,3,7,27,35abc,36abc,39,40,45

13,15bf,16bd,19,20,49,59

13

1,2,13,14,15,19,33,41

4,22ac,27,28,29,39,40,47abde,48bcd

14

1,3,4,6,25,49,51,62,63,67

15,19,23,28,30,46abcd,57,59,69

16

5,6,11,13,19,21,27,28,29,35,47,57,62

3,7,9,17,25,39,44,51,59,68

18

3,5,7,11,31,46,76,82

9,17,19,29,30,34,38myway,44,80

14.5

31,32,33,37

 

10

7,8,9,13,19,31,33,35,40,41,49,63,67

26ab,27,61,62,66,100

 

 

 

19 amino acids & proteins

(When needed, look up R groups and draw at pH 7 unless otherwise noted)

1,7,8,29,30,33,34,35,39,40,49,50,69

5,14,16abd,19ab@pH7,23,31abc,37,52,53@pH7,59,66

20 enzymes

4,7,9,11,15,19,23,33,34,53,55,58,66,67,72,83,91

 

25,27,31,37ac,38b,46,69,85

from Campbell text:  p. 176-177 questions # 6,8,9,10,22,23

8  solutions

2,5,33,35,37,40,43,44,45,47,50,53,55,70, 71,73,74,75,77,78,79,85,97,101,103,105, 107,109, 11,13,17,19

110

22 cells&

bioenergetics

6,9,10,13,14,15,16,67,69,70,73,75,76

 

15 CHO

5,6,7,8,9,10,14,20,27,28,33,38,41,42,43, 48,50,60bcd

25,29,30,52,57,59

22 CHO metab I

17,23,25,30,31,32,33,34,37, (essays:39,41,42,43,49,50,53,54,56,89,91,101,102,103) 57,58,60,66,79,80,81,83,85,86,87,93,94, 95,96,97,98,104

27,69,72,74

23 CHO metab II

2,3,4,5,6,7,8,9,10,12,13,14,15,16,19,22,25, 27,29,30,31,47,48,49,50,51,52,53,54,55,56, 57,58,62,63,64,65,66,67,68,69,71,79,80

35,39,40,45,61,72,74,75,81,92

 

 

 

17 lipids

3,6,11,17,18,70,74,81,85,86 (essays:41,49,51,53,61,62,64,69)

21,31,34

24 lipid metab

7,9,11,14,16,17,18,21,25,26,69,71,72,80,82 (essays:1,2,3,43)

12,59,60,62,64

24 amino acids

35,37,38,51abd,53,56,57

39,40,45

21 DNA/RNA

1,2,3,7,17,23,24,28,29,30,39,40,47,48,51,52, 59,71,77,105    (essays:11,12,20,22,31,32,37,41, 42,43,44,54,55,58,64,75,76)

9,14 (using letter codes for bases),62

 


 

CHEM 201 LABORATORY

 

Laboratory is a concurrent requirement of Chemistry 201.  It is designed to illustrate chemical and biochemical principles and teach fundamental techniques.

 

 

REQUIRED MATERIALS:

Lab Texts:       Biochemistry Class Notes & Labs, Dr. Annie Bianchino, Fall 2014.  All experiments and safety information are in this package available at the FC bookstore.

 

Supplies:  Scientific Calculator  (with scientific notation and logs)

                  Safety Goggles

                  Fullerton College Computer Access 

 

RECOMMENDED MATERIALS:

            pot holder or small towel,   lab apron or lab coat.

 

GUIDELINES FOR SUCCESS:

 

            Be prompt and regular in attendance.  Excessive absences or tardiness will result in a lower grade.  Quizzes may be given at the beginning of the lab period.  If you are late, you will not be allowed to make up that quiz; you will get a score of zero instead.

 

            There are generally NO MAKE UP LABS.  You receive a zero score for each missed lab.  That really hurts your grade.  If you must miss a lab, see the instructor ASAP.

 

            Be prepared for the laboratory experiment.  Read the experiment before lab; it will save you time and frustration and you will get a better grade!  Remember that you only have 1 1/2 hours for lab, so if you are not prepared, you will not be able to complete the experiment and your grade on that experiment will be reduced proportionally.

 

            Do not expect to spend the lab time working on the reports for previous experiments.  Lab reports should be completed at home, outside of class time.  If you need help, contact the instructor via office hours, email, or on a message board on MyGateway.

 

            Avoid collaboration on laboratory experiments and reports except by instructor assignment.  Falsification of data and/or collaboration may result in zeros for all students involved.  Copied answers to questions will receive no credit for anyone involved.

 

            Try to master each new technique and principle as it is presented.  You will use certain techniques throughout the course and in other science courses.  Your lab instructor is here to assist you.


LAB REPORTS: 

            Lab report scores will be worth a total of 100 points (based on a %) toward your overall grade in the course.

            Most lab reports will be due at the end of the Thursday lab period.  Some labs are simple data sheets and questions to answer; other labs may be more like a formal report.  Whether a formal report is due will be announced at the beginning of the lab.

            The formal reports and reports that include graphing will require more time to finish, and will be due at the beginning of the following lab period.  This will be announced during the lab prep discussion.

            Most lab report are worth a 10 points each; more detailed reports are worth 20 points.  The enzyme lab report (formal report) is worth 60 points.

            Late lab reports will generally NOT be accepted.

 

LAB QUIZZES:

            “Pop” lab quiz scores will be worth a total of 100 points (based on a %) toward your overall grade in the course.  These will really make a difference in your lab grade!

            Unannounced quizzes will be given from time to time.  Quizzes may cover material to be done that same day, to check to see if you have read the experiment and understand the basic ideas.  The final lab quiz will be scheduled during the last week of classes, and is worth more than a regular quiz.

            Quizzes may also cover material from an experiment that was performed the previous week or two, to see if you understood what it was all about.

            Quizzes will be given at the start of lab.  If you come in late and miss the short quiz, then you receive a score of zero.  NO make up quizzes!

 

NOTE REGARDING LABS:

            All lab experiments are in your class notes package purchased at the bookstore, or will be given as handouts. 

            Chem 201 is a course that is constantly revised, and many of the labs are still in a state of development.  Some of the things may not always work as well as we hope.  Be patient.  If you have suggestions or comments, talk to your instructor.  Thanks.

 

 

SAFETY:

All safety rules and procedures must be adhered to at all times.  These safety rules are shown the first day of lab in the safety video and are discussed during the first week of classes.                        Safety goggles may be purchased at the bookstore or elsewhere and must protect the eyes from the top and sides.  Eyeglasses, sunglasses and safety shields are not sufficient.  You MUST have goggles and WEAR THEM correctly or you will not be allowed to participate in laboratory classes.  Points will be deducted from lab if you need to be told to wear your goggles.

 

Check In and Check Out:

            Once you check in to a “locker”, YOU are responsible for the equipment in that locker.  Be sure all items are present at the start, and that they are not chipped or broken. 

            At the end of the semester you will check out of the locker.  At that time I will inspect each piece of equipment and you will need to replace anything that is lost or broken.  You may be charged for broken or lost equipment.

            If you drop the course, you MUST check out of your locker. 


Chem 201

Tentative Lab Schedule

 

Week

Exp #

Experiment

 

 

 

  1

 

 

Safety & Computer Lab Exercises

Organic Chem models I & II

Check In to lockers

  2

Models

Organic Chem models I & II & III continued

More Computer Lab Exercises

  3

A

intro to small scale

O Chem functional groups: alcohols, aldehydes, ketones, and esters

  4

B

pH, Acid, Bases, Titrations

  5

C

D

amino acid titration, complete all titrations

buffers

  6

p.L59

 

amino acids and proteins

 

  7

F

 

(E)

ELISA determination of HIV antibodies (simulated; no human blood used) -Thursday

Discussion of enzyme lab

  8

E

enzymes  (amylase w temp, pH, Cu, enz)

  9

G

Urine analysis (simulated)

DO NOT bring in your own samples

  10

H

Spectrophotometry and dilutions

  11

I

protein assay/amount of protein in milk

  12

J

K

L

vitamin C in juice

metabolism exercise

lab discussion for exp L, GFP experiment

  13

L

 

L, K

grow recombinant bacteria

(also meet Wed 1hr TBA)

Collect bacteria, and more metabolism exercise

  14

L

isolate and purify glow protein, GFP

Thanksgiving Holiday

  15

J

UV beads and Check-Out of Lockers and complete clean up of GFP lab

Lab Final

  16

 

Lecture review

Lecture Final Exam (no lab meeting)

 

Useful info:         Your box #                                     

                             Your lab partner:  (Name & number/email)                                                                       

 

Chem 201 lab grade calculation:

 

 

 

Lab Report Scores:

 

Exp #

models

A

B,C

D

AA

F

E

G

H

I

J

K

L

Total

Score

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Possible pts

20

10

20

10

10

10

60

10

10

10

10

10

10

200

 

 

To calculate your lab report score, calculate the percentage that you obtained from all the possible points (190) after dropping your lowest score.  This will be your score out of 100 points.

 

 

Lab Quiz Scores:

 

At this time no one knows how many quizzes will be given, keep track of your scores and the total number of possible points.  Remember, if you miss a quiz, you will get a zero for that one and it will definitely affect your grade.

 

 

Quiz #

1

2

3

4

5

6

Lab

Final

Total

Score

 

 

 

 

 

 

 

 

 

Possible pts

 

 

 

 

 

 

 

 

 

To calculate your lab quiz score, calculate the percentage that you obtained from all the possible points after dropping your lowest score.  This will be your score out of 100 points.